A client taking nefazodone hydrochloride (Serzone) is likely to have a history of which condition?

Nefazodone hydrochloride, marketed under the brand name Serzone, is primarily used as an antidepressant. It is part of the class of medications known as serotonin antagonists and reuptake inhibitors (SARIs). Given its specific indication for treating depression, a client taking nefazodone is most likely to have a history of this condition.

Depression often leads individuals to seek treatment with medications like nefazodone, which can help alleviate symptoms such as persistent sadness, hopelessness, and lack of interest in activities. The medication works by altering the balance of neurotransmitters in the brain, particularly serotonin.

The other options, while they represent significant health conditions, do not have a direct link to the use of nefazodone. Diabetes mellitus, hyperthyroidism, and coronary artery disease could potentially co-occur with depression but are not conditions for which nefazodone would typically be prescribed. Therefore, the presence of a history of depression aligns directly with the client’s use of nefazodone.